Colonoscopy with Suprep

Download the Instructions as PDF


There are many things a person would rather do than undergo a bowel prep for a colonoscopy, but your efforts at cleansing your colon are essential for an accurate procedure. These instructions are designed to maximize the ease, safety and success of your preparation. Please read these instructions carefully at least one week prior to your exam. Obtain SUPREP Bowel Prep Kit from your pharmacist (Note: this requires a prescription).

Medication and Diet Instructions:


  1. If you take aspirin (and or aspirin containing products), Plavix, Eliquis or any other medication which may influence your ability to clot, please get specific instructions from your doctor about when or if you must stop these medications prior to your procedure.


  1. If you take Coumadin (warfarin) for a heart valve please speak to your prescribing cardiologist about alternatives prior to your procedure.
  2. If you take non-steroidal anti-inflammtories (NSAIDS; Advil, Motrin, Aleve), please discontinue three days prior to your exam. You may use Tylenol as an alternative if needed for pain.
  3. Avoid eating nuts, seeds, popcorn, grapes, green peas, beans and tomatoes. Fibers from these foods can clog the colonoscope.


You may have a regular breakfast. After breakfast, you will need to go on a clear liquid diet. You can drink clear liquids up to 2 hours prior to the appointment. Avoid juices with pulp such as orange or grapefruit juice. No dairy products, cream or soy. Coffee and tea are O.K. Examples of clear liquids include broth or bouillon, Jell-O, clear juices (white grape or apple), sports drinks such as Gatorade or Powerade, sodas such as Sprite, 7-Up, or ginger ale, lemonade, Popsicles, coffee or tea and of course, water. Avoid red or purple colored liquids. You may use sugar, honey or lemon. It is important that you drink as much fluid as you can throughout the day. It is also worthwhile to get a supply of aloe wet wipes and Desitin ointment to ward off a sore bottom.

The SUPREP Bowel Prep Kit contains two 6-ounce bottles of liquid bowel prep and one 16 ounce mixing container. You must complete the entire prep to ensure the most effective cleansing.


Step 1:



Pour ONE (1) 6-ounce bottle of SUPREP liquid into the mixing container.

Step 2:



Add cool drinking water to the 16-ounce line on the container and mix.

Step 3:



Drink ALL the liquid in the container.

Step 4:



You MUST drink two (2) more 16-ounce containers of clear liquid of your choice over the next 1 hour.

If your procedure is before 11am, take the first dose of prep at 12pm, then the second dose at 8pm the day before your exam.  If your procedure is at or after 11am, take the first dose at 8pm the day before your exam and the second dose at 5am on the day of your procedure.


  • Do not drink anything 2 hours before the procedure.
  • You must be accompanied by a friend or relative to drive or assist you home. You will not be allowed to drive for 12 hours after the procedure.
  • You should take your regular medications with sips of water unless you are instructed otherwise.

Special Instructions:

  • If you are a diabetic taking insulin, hold the morning dose of insulin the day of the procedure
  • Be sure to remember any allergies to medications and to Latex, or conditions that would make you sensitive to sedation such as sleep apnea syndrome.

Commonly Asked Questions:

How do I know if my colonoscopy prep is successful?

The stool should be watery in consistency. It does not have to be clear in color like water since digestive juices will continue to tint the stool yellow and small flecks of debris are not a problem as long as the stool is not muddy or thick. If there is any question, you can self administer a fleet enema prior to leaving home for the procedure.

What side effects may I expect?

Since the prep works by flooding the intestinal tract with fluid, abdominal bloating and cramping may occur, as well as some nausea and vomiting. This is usually temporary, and as the diarrhea develops, symptoms will gradually improve. Weakness can also occur, especially if you have not taken enough fluid with the prep, and can be remedied by increasing fluid intake (especially with the sports drinks such as Gatorade or Powerade).

Will the prep interfere with my other medications?

Medications taken at least an hour before beginning the prep should be adequately absorbed, but thereafter, they are likely to be washed away by the prep.

What if I have other questions?

Call our office to address any other concerns not answered here.

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